Deuan C. Jones

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography

Stephen Patterson, M.S. Alphey, Deuan C. Jones et al. · Journal of Medicinal Chemistry · 2011 · 130 citations · Full text

Protein Crystallography, Bioorganic Chemistry, Antiparasitic Agent +18

Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis

Deuan C. Jones, Irene Hallyburton, Laste Stojanovski et al. · Biochemical Pharmacology · 2010 · 72 citations · Full text

Drug Target, Lopac 1280, Immunology +21

Improved Tricyclic Inhibitors of Trypanothione Reductase by Screening and Chemical Synthesis

John L. Richardson, Isabelle Nett, Deuan C. Jones et al. · ChemMedChem · 2009 · 69 citations · Full text

Combinatorial Chemistry, Antiparasitic Agent, Pharmacotherapy +17

Deletion of the Glucosidase II Gene in Trypanosoma brucei Reveals Novel N-Glycosylation Mechanisms in the Biosynthesis of Variant Surface Glycoprotein

Deuan C. Jones, Angela Mehlert, Maria Lucia S. Güther et al. · Journal of Biological Chemistry · 2005 · 67 citations · Full text

Glycobiology, Molecular Biology, Molecular Genetics +17

Comparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruzi

Deuan C. Jones, A. Ariza, Wing-Huen A. Chow et al. · Molecular and Biochemical Parasitology · 2009 · 60 citations · Full text