L.B. Tulloch

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

Antonio Cavazzuti, Giuseppe Paglietti, William N. Hunter et al. · Proceedings of the National Academy of Sciences · 2008 · 157 citations · Full text

Crystal Structure, Bioorganic Chemistry, Antiparasitic Agent +17

One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening

Chidochangu P. Mpamhanga, Daniel Spinks, L.B. Tulloch et al. · Journal of Medicinal Chemistry · 2009 · 105 citations · Full text

Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases

L.B. Tulloch, Viviane Paula Martini, J. Iulek et al. · Journal of Medicinal Chemistry · 2009 · 86 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Pharmacotherapy +17

The Inhibitory Effect of Phospholemman on the Sodium Pump Requires Its Palmitoylation

L.B. Tulloch, J. W. Howie, Krzysztof Wypijewski et al. · Journal of Biological Chemistry · 2011 · 76 citations · Full text

Structure and reactivity of <i>Trypanosoma brucei</i> pteridine reductase: inhibition by the archetypal antifolate methotrexate

Alice Dawson, Federica Gibellini, Natasha Sienkiewicz et al. · Molecular Microbiology · 2006 · 64 citations · Full text