Catherine Yuan

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 655 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Structure–Activity Relationships and Discovery of a G Protein Biased μ Opioid Receptor Ligand, [(3-Methoxythiophen-2-yl)methyl]({2-[(9<i>R</i>)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the Treatment of Acute Severe Pain

Xiaotao Chen, Philip Pitis, Guodong Liu et al. · Journal of Medicinal Chemistry · 2013 · 203 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

David Payne, William H. Miller, Valerie Berry et al. · Antimicrobial Agents and Chemotherapy · 2002 · 165 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Dirk A. Heerding, George Chan, Walter E. DeWolf et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic

William H. Miller, Doreen Alberts, Pradip K. Bhatnagar et al. · Journal of Medicinal Chemistry · 1999 · 117 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7