Lucy Mensah

GSK2578215A; A potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor

Alastair D. Reith, Paul Bamborough, Karamjit S. Jandu et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 149 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +11

The antimicrobial natural product chuangxinmycin and Some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase

Murray J. B. Brown, Paul S. Carter, Ashley Fenwick et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 138 citations

Natural Product Synthesis, Antibiotics, Medicine +10

Analogues of SB-203207 as inhibitors of tRNA synthetases

Martin G. Banwell, Curtis F. Crasto, Christopher J. Easton et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 79 citations · Full text

Medicine, Trna Synthetases, Pharmacology +2

Rational Design of Femtomolar Inhibitors of Isoleucyl tRNA Synthetase from a Binding Model for Pseudomonic Acid-A

Murray J. B. Brown, Lucy Mensah, Michael L. Doyle et al. · Biochemistry · 2000 · 76 citations

Crystal Structure, Bioorganic Chemistry, Molecular Biology +23

Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases

Andrew K. Forrest, Richard L. Jarvest, Lucy Mensah et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 67 citations · Full text

Cognate Staphylococcus, Biochemistry, Natural Sciences +9