Alastair D. Reith

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Gareth J. Inman, Francisco José Nicolás, James F. Callahan et al. · Molecular Pharmacology · 2002 · 1.7K citations

Life Sciences, Molecular Biology, Pharmacology +13

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

Martin Steger, Francesca Tonelli, Genta Ito et al. · eLife · 2016 · 1.1K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

Matthew P. Coghlan, Ainsley A. Culbert, Darren A.E. Cross et al. · Chemistry & Biology · 2000 · 895 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization

Nicolas Dzamko, Mária Deák, Fayçal Hentati et al. · Biochemical Journal · 2010 · 388 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

Darren A.E. Cross, Ainsley A. Culbert, Katy Chalmers et al. · Journal of Neurochemistry · 2001 · 366 citations

Life Sciences, Biochemistry, Neuroscience +17