Hypothalamic malonyl-CoA as a mediator of feeding behavior

Zhiyuan Hu, Seung Hun, Shigeru Chohnan, +1

Proceedings of the National Academy of Sciences

Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

Su Gao, Kimberly P. Kinzig, Susan Aja, +13

Proceedings of the National Academy of Sciences

NutritionFood IntakeHypothalamic CircuitsGastrointestinal Peptide HormoneMetabolic Syndrome +14

Differential effects of central fructose and glucose on hypothalamic malonyl–CoA and food intake

Seung Hun, Michael J. Wolfgang, Yuka Tokutake, +2

Proceedings of the National Academy of Sciences

NutritionFood IntakeHypothalamic CircuitsExperimental NutritionInsulin Signaling +18

Regulation of hypothalamic malonyl-CoA by central glucose and leptin

Michael J. Wolfgang, Seung Hun, Aniket Sidhaye, +4

Proceedings of the National Academy of Sciences

A Role for Hypothalamic Malonyl-CoA in the Control of Food Intake

Zhiyuan Hu, Yun Dai, Marc Prentki, +2

Journal of Biological Chemistry

NutritionFood IntakeVentral HypothalamusGastrointestinal Peptide HormoneNeuroendocrine Mechanism +17

Chemical Knockout of Pantothenate Kinase Reveals the Metabolic and Genetic Program Responsible for Hepatic Coenzyme A Homeostasis

Yong-Mei Zhang, Shigeru Chohnan, Kristopher G. Virga, +8

Chemistry & Biology

Genetic Program ResponsibleBiochemistryMedicineLiver PhysiologyMetabolic Regulation +9

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

Iori Sakakibara, Takahiro Fujino, Makoto Ishii, +21

Cell Metabolism

Energy HomeostasisEnergy MetabolismBiochemistryPhysiologyHomeostatic Mechanism +8

A Pantothenate Kinase from Staphylococcus aureus Refractory to Feedback Regulation by Coenzyme A

Roberta Leonardi, Shigeru Chohnan, Yong-Mei Zhang, +4

Journal of Biological Chemistry

Molecular RegulationBacteriologyCoenzyme AMolecular BiologyChemical Biology +16

Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle

Seung Hun, Zhiyuan Hu, Shigeru Chohnan, +1

Proceedings of the National Academy of Sciences

Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria

Shigeru Chohnan, H Furukawa, Tooru Fujio, +2

Applied and Environmental Microbiology

Intracellular LevelsCoa PoolsEngineeringBiological Carbon FixationBiochemistry +12