Hypothalamic malonyl-CoA as a mediator of feeding behavior

Zhiyuan Hu, Seung Hun, Shigeru Chohnan, +1

Proceedings of the National Academy of Sciences

The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis

Michael J. Wolfgang, Takeshi Kurama, Yun Dai, +6

Proceedings of the National Academy of Sciences

Metabolic RemodelingOxidative StressMetabolic SyndromeFatty AcidsCpt1c Ko Mice +17

Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity

Woo Sik Kim, Yun Sok Lee, Seung Hun, +8

American Journal of Physiology-Endocrinology and Metabolism

Metabolic DisorderAmpk ActivityInsulin SignalingOxidative StressObesity +17

Differential effects of central fructose and glucose on hypothalamic malonyl–CoA and food intake

Seung Hun, Michael J. Wolfgang, Yuka Tokutake, +2

Proceedings of the National Academy of Sciences

NutritionFood IntakeHypothalamic CircuitsExperimental NutritionInsulin Signaling +18

Amino Acid Signaling to mTOR Mediated by Inositol Polyphosphate Multikinase

Seyun Kim, Sangwon F. Kim, David Maag, +9

Cell Metabolism

Protein FunctionSignal TransductionSignaling PathwayBiochemistryAmino Acid +9

Regulation of hypothalamic malonyl-CoA by central glucose and leptin

Michael J. Wolfgang, Seung Hun, Aniket Sidhaye, +4

Proceedings of the National Academy of Sciences

Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle

Seung Hun, Zhiyuan Hu, Shigeru Chohnan, +1

Proceedings of the National Academy of Sciences

Brain‐specific carnitine palmitoyl‐transferase‐1c: role in CNS fatty acid metabolism, food intake, and body weight

Michael J. Wolfgang, Seung Hun, David S. Millington, +7

Journal of Neurochemistry

Food IntakeBrain NutritionMetabolic RemodelingSocial SciencesOxidative Stress +26

Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway

Seung Hun, M. Daniel Lane

Biochemical and Biophysical Research Communications

NutritionFood IntakeObesityMetabolic SyndromeMetabolic Signaling +14

Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects

Zhiyuan Hu, Seung Hun, Goedelle van Haasteren, +2

Proceedings of the National Academy of Sciences