Amanda Balboni Iniguez

EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

Aparna Gorthi, July Carolina Romero, Eva Loranc et al. · Nature · 2018 · 324 citations · Full text

Transcriptional Regulation, Ewing Sarcoma, Medicine +8

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia et al. · Nature Genetics · 2018 · 291 citations · Full text

Transcriptional Regulation, Systems Biology, Glioma +7

EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma

Amanda Balboni Iniguez, Björn Stolte, Emily Jue Wang et al. · Cancer Cell · 2018 · 167 citations · Full text

Tumor Biology, Ewing Sarcoma, Medicine +8

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2

Liying Chen, Gabriela Alexe, Neekesh V. Dharia et al. · Journal of Clinical Investigation · 2017 · 156 citations · Full text

Glioma, Crispr-cas9 Screen, Medicine +14

STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

Biniam Adane, Gabriela Alexe, Bo Kyung A. Seong et al. · Cancer Cell · 2021 · 114 citations · Full text

Ewing Sarcoma, Medicine, Pathology +7