Elena T. Chan

Interactions between traditional Chinese medicines and Western therapeutics.

Elena T. Chan, Marisela Tan, Jianni Xin et al. · PubMed · 2010 · 216 citations

Traditional Chinese, Traditional Medicine, Translational Medicine +15

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

N. Franke, Denise Niewerth, Yehuda G. Assaraf et al. · Leukemia · 2011 · 170 citations

Hematological Malignancy, Protein Function, Natural Sciences +9

Reactive glia show increased immunoproteasome activity in Alzheimer’s disease

Marie Orre, Willem Kamphuis, Stephanie Dooves et al. · Brain · 2013 · 168 citations

Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

Sue Ellen Verbrugge, Yehuda G. Assaraf, Ben A. C. Dijkmans et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 107 citations

Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer

Leonie H.A.M. de Wilt, Gerrit Jansen, Yehuda G. Assaraf et al. · Biochemical Pharmacology · 2011 · 80 citations

Medicine, Molecular Biology, Cancer Biology +7