Concepedia

Denise Niewerth

DN

11

Publications

500

Citations

10

H-Index

2011

Active since

Affiliations

Amsterdam UMC Location Vrije Universiteit Amsterdam(Current)

Technion – Israel Institute of Technology

Children's Cancer Center

Baylor College of Medicine

Stichting Kinderoncologie Nederland

Denise Niewerth is an author at Amsterdam UMC Location Vrije Universiteit Amsterdam specializing in medicine, immunology, and immunotherapy.

ORCID

Top concepts

Publications per year

2011–2018

11

Publications

11

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

N. Franke, Denise Niewerth, Yehuda G. Assaraf et al. · Leukemia · 2011 · 170 citations

, , +9

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

Denise Niewerth, Gertjan J.L. Kaspers, Yehuda G. Assaraf et al. · Journal of Hematology & Oncology · 2014 · 70 citations · Full text

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

Denise Niewerth, N. Franke, Gerrit Jansen et al. · Haematologica · 2013 · 64 citations · Full text

Antileukemic Activity and Mechanism of Drug Resistance to the Marine Salinispora tropica Proteasome Inhibitor Salinosporamide A (Marizomib)

Denise Niewerth, Gerrit Jansen, Lesley F. V. Riethoff et al. · Molecular Pharmacology · 2014 · 43 citations · Full text

Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924

Denise Niewerth, Johan van Meerloo, Gerrit Jansen et al. · Biochemical Pharmacology · 2014 · 39 citations

, , +7

Rows per page

1–5 of 11