A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.

Thomas Hünig, Hans‐Joachim Wallny, Jordan Hartley, +2

The Journal of Experimental Medicine

Rat ThymusAdaptive Immune SystemT-regulatory CellImmunologyImmunologic Mechanism +17

Alternative pathway activation of T cells by binding of CD2 to its cell-surface ligand

Thomas Hünig, Georg Tiefenthaler, K. H. Meyer zum Büschenfelde, +1

Nature

Signal TransductionT CellsT-regulatory CellImmunologyAlternative Pathway Activation +9

Differential thymus dependence of rat CD8 isoform expression

Nora Torres‐Nagel, Elmar Kraus, Marion H. Brown, +3

European Journal of Immunology

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities

Steven Cho, Ina Rudloff, Jason Chun Lao, +29

Nature Communications

Brain Shuttle Antibody for Alzheimer’s Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode

Felix Weber, Bernd Bohrmann, Jens Niewoehner, +10

Cell Reports

CART: a conserved antigen receptor transmembrane motif

Kerry S. Campbell, B. Thomas Bäckström, Georg Tiefenthaler, +1

Seminars in Immunology

Signal TransductionMolecular PhysiologyImmunologyReceptor (Biochemistry)Antigen Processing +3

Prospects of bacterial and plant protein-based immunotoxins for treatment of cancer.

Ulrich H. Weidle, Georg Tiefenthaler, Christian Schiller, +3

PubMed

ImmunotoxicologyToxinologyImmunologyImmunoeditingBiological Therapy +16

The emerging role of new protein scaffold-based agents for treatment of cancer.

Ulrich H. Weidle, Johannes Auer, Ulrich Brinkmann, +2

PubMed

Amino AcidsImmunologyPeptide ScienceNew Protein-based ScaffoldsTumor Biology +15

The Blood-Brain Barrier Challenge for the Treatment of Brain Cancer, Secondary Brain Metastases, and Neurological Diseases.

Ulrich H. Weidle, Jens Niewöhner, Georg Tiefenthaler

PubMed

EngineeringVarious Tumor EntitiesHigh-grade GliomasBiomedical EngineeringBrain Lesion +21

A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood

Stefan Seeber, Francesca Ros, Irmgard S. Thorey, +12

PLoS ONE

Immunocytochemical TechniqueRabbit BloodLaboratory ImmunologyImmunologyPathology +16