Brett J. Prigaro

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

Anila K. Madiraju, Derek M. Erion, Yasmeen Rahimi et al. · Nature · 2014 · 1.3K citations

Life Sciences, Biochemistry, Endocrinology +12

Pre-mRNA Splicing-Modulatory Pharmacophores: The Total Synthesis of Herboxidiene, a Pladienolide–Herboxidiene Hybrid Analog and Related Derivatives

Chandraiah Lagisetti, Maria V. Yermolina, Lalit Kumar Sharma et al. · ACS Chemical Biology · 2013 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase

Yili Ding, Jean‐Luc Girardet, Kenneth L. Smith et al. · Bioorganic Chemistry · 2005 · 54 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +13

Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase

Yili Ding, Jean‐Luc Girardet, Kenneth L. Smith et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 34 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

Brett J. Prigaro, Hector Esquer, Qiong Zhou et al. · Journal of Medicinal Chemistry · 2022 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13