Jean‐Luc Girardet

Mononucleoside Phosphotriester Derivatives with S-Acyl-2-thioethyl Bioreversible Phosphate-Protecting Groups: Intracellular Delivery of 3'-Azido-2',3'-dideoxythymidine 5'-Monophosphate

Isabelle Lefèbvre, Christian Périgaud, Alain Pompon et al. · Journal of Medicinal Chemistry · 1995 · 232 citations

Pharmacy, Biochemistry, Pharmacology +8

Design, Synthesis, and Antiviral Activity of α-Nucleosides:  <scp>d</scp>- and <scp>l</scp>-Isomers of Lyxofuranosyl- and (5-Deoxylyxofuranosyl)benzimidazoles

Michael T. Migawa, Jean‐Luc Girardet, John Walker et al. · Journal of Medicinal Chemistry · 1998 · 212 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

Jeffrey N. Miner, Philip K. Tan, David Hyndman et al. · Arthritis Research & Therapy · 2016 · 124 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Rational design for cytosolic delivery of nucleoside monphosphates : “SATE” and “DTE” as enzyme-labile transient phosphate protecting groups

Christian Périgaud, Gilles Gosselin, Isabelle Lefèbvre et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 114 citations

Life Sciences, Biochemistry, Molecular Biology +11

Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase

Martha De la Rosa, Hong Woo Kim, Esmir Gunić et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 110 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14