Enrico L. DiGiammarino

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 858 citations · Full text

Medicine, Cancer Biology, Oncology +8

A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

Enrico L. DiGiammarino, Amanda S. Lee, Craig Cadwell et al. · Nature Structural Biology · 2001 · 289 citations

Medicine, Cancer Biology, Molecular Biology +11

Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex

Jason D. Weber, Mei-Ling Kuo, Brian Bothner et al. · Molecular and Cellular Biology · 2000 · 278 citations

Life Sciences, Molecular Biology, Oncology +15

Mechanistic Dissection of PARP1 Trapping and the Impact on <i>In Vivo</i> Tolerability and Efficacy of PARP Inhibitors

Todd A. Hopkins, Yan Shi, Luis E. Rodrı́guez et al. · Molecular Cancer Research · 2015 · 267 citations

Medicine, Oncology, Pharmacology +17

PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow

Todd A. Hopkins, William B. Ainsworth, Paul A. Ellis et al. · Molecular Cancer Research · 2018 · 256 citations

Medicine, Oncology, Pharmacology +13