Concepedia
Statistics
Publications
25
Citations
2.8K
H-Index
22
Active since
1998
Affiliations
AbbVie (United States)(Current)
St. Jude Children's Research Hospital
University of Tennessee at Knoxville
University of Tennessee Health Science Center
BioPAL (United States)
Enrico L. DiGiammarino is an author at AbbVie (United States) specializing in medicine, cell biology, and molecular biology.
Top concepts
MedicineCell BiologyTumor BiologyMolecular BiologyImmunologySystems BiologyBiochemistryImmunotherapyCell SignalingCancer Research
Publications per year
1998–2022
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Loren Lasko, Clarissa G. Jakob, Rohinton Edalji et al. · Nature · 2017 · 813 citations · Full text
Lineage-specific Tumours, Medicine, Immune Checkpoint Inhibitor +8
A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer
Enrico L. DiGiammarino, Amanda S. Lee, Craig Cadwell et al. · Nature Structural Biology · 2001 · 288 citations
Ph-dependent Destabilization, Novel Mechanism, Oncogenic Agent +9
Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex
Jason D. Weber, Mei-Ling Kuo, Brian Bothner et al. · Molecular and Cellular Biology · 2000 · 278 citations · Full text
Molecular Regulation, Magnetic Resonance, Molecular Biology +19
Mechanistic Dissection of PARP1 Trapping and the Impact on <i>In Vivo</i> Tolerability and Efficacy of PARP Inhibitors
Todd A. Hopkins, Yan Shi, Luis E. Rodrı́guez et al. · Molecular Cancer Research · 2015 · 257 citations
PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow
Todd A. Hopkins, William B. Ainsworth, Paul A. Ellis et al. · Molecular Cancer Research · 2018 · 250 citations
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