Todd A. Hopkins

Mechanistic Dissection of PARP1 Trapping and the Impact on <i>In Vivo</i> Tolerability and Efficacy of PARP Inhibitors

Todd A. Hopkins, Yan Shi, Luis E. Rodrı́guez et al. · Molecular Cancer Research · 2015 · 257 citations

PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow

Todd A. Hopkins, William B. Ainsworth, Paul A. Ellis et al. · Molecular Cancer Research · 2018 · 250 citations

<i>In Vitro</i> and <i>In Vivo</i> Antiviral Activity and Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor ABT-450

Rakesh Tripathi, Daniel E. Cohen, I. Gaultier et al. · Antimicrobial Agents and Chemotherapy · 2014 · 116 citations · Full text

Cytochrome P450 3A4, Viral Hepatitis, Medicine +13

<i>In Vitro</i> Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir

Teresa I. Ng, Rakesh Tripathi, Thomas Reisch et al. · Antimicrobial Agents and Chemotherapy · 2017 · 87 citations · Full text

Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses

Roger J. Brideau, Mary L. Knechtel, Audris Huang et al. · Antiviral Research · 2002 · 77 citations

Broad-spectrum Antiviral Activity, Biochemistry, Animal Herpesviruses +8