A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

Dallas R. Donohoe, Darcy Holley, Leonard B. Collins, +13

Cancer Discovery

Reactive oxygen species reprogram macrophages to suppress antitumor immune response through the exosomal miR-155-5p/PD-L1 pathway

Xiang Li, Shaomin Wang, Wei Mu, +9

Journal of Experimental & Clinical Cancer Research

IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB

Susan J. Burke, Krisztián Stadler, Danhong Lu, +7

American Journal of Physiology-Endocrinology and Metabolism

Diabetes DevelopmentImmunologyImmune RegulationInsulin SignalingInflammation +20

Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases

Anna Han, Natalie E. Bennett, Ahmed Bettaieb, +2

Oncotarget

ChromatinHistone DeacetylasesChemoprevention StrategyBiochemistryOncogenic Agent +12

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Anna Han, Timothy J. Purwin, Nelisa Bechtel, +8

Oncogene

Distinct VulnerabilityMedicinePhotocarcinogenesisMelanomaMetabolic Phenotypes +5

Association of Dietary Total Antioxidant Capacity with Bone Mass and Osteoporosis Risk in Korean Women: Analysis of the Korea National Health and Nutrition Examination Survey 2008–2011

Donghyun Kim, Anna Han, Yongsoon Park

Nutrients

The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)

Vivian Chua, Jane Mattei, Anna Han, +6

Clinical Cancer Research

Ocular DiseaseEngineeringPathologyDermatologyRetinal Therapies +20

Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells

Anna Han, Natalie E. Bennett, Amber MacDonald, +3

Journal of Cellular Physiology

Chemoprevention StrategyLipid PeroxidationDietary FibreOxidative StressCellular Metabolism +14

Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma

Jessica L.F. Teh, Timothy J. Purwin, Anna Han, +9

Molecular Cancer Therapeutics

Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma

Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, +6

Molecular Cancer Research