David B. Bolstad

Crystal Structures of Wild-type and Mutant Methicillin-resistant Staphylococcus aureus Dihydrofolate Reductase Reveal an Alternate Conformation of NADPH That May Be Linked to Trimethoprim Resistance

Kathleen M. Frey, Jieying Liu, Michael N. Lombardo et al. · Journal of Molecular Biology · 2009 · 57 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Structure-Guided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase

Jieying Liu, David B. Bolstad, Adrienne E. Smith et al. · Chemistry & Biology · 2008 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting <i>Bacillus anthracis</i> Dihydrofolate Reductase

Jennifer M. Beierlein, Kathleen M. Frey, David B. Bolstad et al. · Journal of Medicinal Chemistry · 2008 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from <i>Cryptosporidium</i>

David B. Bolstad, Erin S. D. Bolstad, Kathleen M. Frey et al. · Journal of Medicinal Chemistry · 2008 · 39 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

Towards New Antifolates Targeting Eukaryotic Opportunistic Infections

Jieying Liu, David B. Bolstad, Erin S. D. Bolstad et al. · Eukaryotic Cell · 2009 · 27 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14