Adrienne E. Smith

Structure-Guided Development of Efficacious Antifungal Agents Targeting Candida glabrata Dihydrofolate Reductase

Jieying Liu, David B. Bolstad, Adrienne E. Smith et al. · Chemistry & Biology · 2008 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthetic and Crystallographic Studies of a New Inhibitor Series Targeting <i>Bacillus anthracis</i> Dihydrofolate Reductase

Jennifer M. Beierlein, Kathleen M. Frey, David B. Bolstad et al. · Journal of Medicinal Chemistry · 2008 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Alternating Pattern of Stereochemistry in the Nonactin Macrocycle Is Required for Antibacterial Activity and Efficient Ion Binding

Brian R. Kusche, Adrienne E. Smith, Michele A. McGuirl et al. · Journal of the American Chemical Society · 2009 · 40 citations · Full text

Pharmacy, Biochemistry, Chemistry +11

Probing the Active Site of <i>Candida glabrata</i> Dihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New Inhibitors

Jieying Liu, David B. Bolstad, Adrienne E. Smith et al. · Chemical Biology & Drug Design · 2008 · 23 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

In vitro biological activity and structural analysis of 2,4-diamino-5-(2′-arylpropargyl)pyrimidine inhibitors of Candida albicans

Janet L. Paulsen, Jieying Liu, David B. Bolstad et al. · Bioorganic & Medicinal Chemistry · 2009 · 17 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17