James E. Sheppeck - Concepedia

Author

James E. Sheppeck

Also Known As

G-Yoon Jamie Im, J. E. II SHEPPECK, J. Sheppeck, James E Sheppeck, James E Sheppeck II, James E. II Sheppeck, James E. Sheppeck, James E. Sheppeck II, James Sheppeck, Robert Solinga

Publications

907

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Bristol-Myers Squibb (Germany)Ironwood Pharmaceuticals (United States)University of California, Irvine Rockefeller University

About

James E. Sheppeck is an author at Bristol-Myers Squibb (United States) specializing in pharmacology, biochemistry, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	11	11	353
2	Medicine	10	11	314
3	Natural Sciences	10	10	329
4	Biomolecular Engineering	4	4	158
5	Engineering	2	2	91

James E. Sheppeck

Publications

645

Citations

H-Index

Page 1

	Year	Citations
A convenient and scaleable procedure for removing the Fmoc group in solution James E. Sheppeck, Heidi Kar, Hui Hong Tetrahedron Letters Scaleable ProcedureFmoc Group	2000	79
Conversion of Allylic Alcohols into Allylic Nitromethyl Compounds via a Palladium-Catalyzed Solvolysis: An Enantioselective Synthesis of an Advanced Carbocyclic Nucleoside Precursor<sup>1</sup> Donald R. Deardorff, Kenneth A. Savin, Craig Justman, The Journal of Organic Chemistry Transient Pi-allylpalladium ComplexesCross-coupling ReactionNovel OrganocatalystsEngineeringBiochemistry	1996	61
Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease Jenny Tobin, Daniel P. Zimmer, Courtney Shea, Journal of Pharmacology and Experimental Therapeutics	2018	59
Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE) James J.‐W. Duan, Lihua Chen, Zhonghui Lu, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryDrug TargetingBiochemistryMedicine	2006	53
Total Synthesis of the Serine/Threonine-Specific Protein Phosphatase Inhibitor Tautomycin<sup>1</sup> James E. Sheppeck, Wen Liu, A. Richard Chamberlin The Journal of Organic Chemistry Central LinchpinBioorganic ChemistryOrganic ChemistryProtein Phosphatase InhibitorMedicinal Chemistry	1997	49
Hydantoins, triazolones, and imidazolones as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE) James E. Sheppeck, John L. Gilmore, Andrew J. Tebben, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryMedicineDrug DiscoveryPharmacotherapy	2007	42
Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase Jessica A. Wales, Cheng‐Yu Chen, Linda Breci, Journal of Biological Chemistry	2017	33
Discovery of novel hydantoins as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE) James E. Sheppeck, John L. Gilmore, Anle Yang, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural Sciences	2006	31
Palladium-assisted route to carbocyclic nucleosides: A formal synthesis of (±)-aristeromycin Donald R. Deardorff, Michael J. Shulman, James E. Sheppeck Tetrahedron Letters EngineeringOrganic ChemistryPalladium-assisted RoutePharmacologySynthetic Chemistry	1989	30
Synthesis of a statistically exhaustive fluorescent peptide substrate library for profiling protease specificity James E. Sheppeck, Heidi Kar, Luke Gosink, Bioorganic & Medicinal Chemistry Letters BiochemistryProtein FoldingNatural SciencesPeptide EngineeringPeptide Library	2000	29

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