Wen Liu

Understanding the function–structure and function–mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

Shunsuke Kato, Shuang-Yin Han, Wen Liu et al. · Proceedings of the National Academy of Sciences · 2003 · 869 citations · Full text

Engineering, Molecular Biology, Function–mutation Relationships +17

A genomics-guided approach for discovering and expressing cryptic metabolic pathways

Emmanuel Zazopoulos, Ke-xue Huang, Alfredo Staffa et al. · Nature Biotechnology · 2003 · 316 citations

Metabolic Network, Functional Genomics, Engineering +14

Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Wen Liu, Steven D. Christenson, Scott Standage et al. · Science · 2002 · 280 citations

Bioorganic Chemistry, Engineering, Enediyne Compound +16

Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

Rijing Liao, Lian Duan, Chun Lei et al. · Chemistry & Biology · 2009 · 181 citations · Full text

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

Yi Yu, Lian Duan, Qi Zhang et al. · ACS Chemical Biology · 2009 · 167 citations · Full text

Bioorganic Chemistry, Engineering, Molecular Biology +17