Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox, +8

Science

Single Crispr ArrayEngineeringShort RnasGeneticsSynthetic Biology +10

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino, +9

Nature

Engineered Crispr-cas9 ComplexTranscriptional RegulationNatural SciencesGenetic EngineeringMolecular Biology +6

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

Schraga Schwartz, Maxwell R. Mumbach, Marko Jovanović, +16

Cell Reports

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyMrna Methylation +20

Massively parallel single-nucleus RNA-seq with DroNc-seq

Naomi Habib, Inbal Avraham‐Davidi, Anindita Basu, +11

Nature Methods

ChromatinNatural SciencesRna Structure PredictionRna BiologyMolecular Biology +4

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

Benjamin R. Carone, Lucas Fauquier, Naomi Habib, +12

Cell

BiologyMedicineGeneticsNatural SciencesGenetic Engineering +8

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

Noa Novershtern, Aravind Subramanian, Lee N. Lawton, +22

Cell

Transcriptional RegulationDevelopmental BiologyCell RegulationMedicineHematology +8

Disease-associated astrocytes in Alzheimer’s disease and aging

Naomi Habib, Cristin McCabe, Sedi Medina, +12

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseaseDisease-associated AstrocytesDegenerative PathologyBrain-immune Interaction +5

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

Lukasz Swiech, Matthias Heidenreich, Abhishek Banerjee, +5

Nature Biotechnology

Knockout MouseOff-target EffectIn Vivo Gene TherapyGenetic EngineeringMammalian Brain +9

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Marta Olah, Vilas Menon, Naomi Habib, +24

Nature Communications

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

Naomi Habib, Yinqing Li, Matthias Heidenreich, +6

Science