Ana Rita Costa

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Tetsuro Murakami, Seema Qamar, Julie Qiaojin Lin et al. · Neuron · 2015 · 920 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structural basis of synaptic vesicle assembly promoted by α-synuclein

Giuliana Fusco, Tillmann Pape, Amberley D. Stephens et al. · Nature Communications · 2016 · 259 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease

Johnny Habchi, Paolo Arosio, Michele Perni et al. · Science Advances · 2016 · 210 citations · Full text

Medicine, Oncology, Pharmacology +17

Transthyretin Protects against A-Beta Peptide Toxicity by Proteolytic Cleavage of the Peptide: A Mechanism Sensitive to the Kunitz Protease Inhibitor

Ana Rita Costa, Frederico Ferreira‐da‐Silva, Maria João Saraiva et al. · PLoS ONE · 2008 · 123 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Testing the Therapeutic Potential of Doxycycline in a Drosophila melanogaster Model of Alzheimer Disease

Ana Rita Costa, Elena Speretta, Damian C. Crowther et al. · Journal of Biological Chemistry · 2011 · 79 citations · Full text

Medicine, Neuroscience, Pharmacology +15