Line Oste

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- <i>a</i> ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis

Nicolas Desroy, Christopher Housseman, Xavier Bock et al. · Journal of Medicinal Chemistry · 2017 · 135 citations · Full text

Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic

Mathieu Pizzonero, Sonia Dupont, Marielle Babel et al. · Journal of Medicinal Chemistry · 2014 · 107 citations · Full text

Inflammation, From Hit, Medicinal Chemistry +15

Effects of Strontium on the Physicochemical Characteristics of Hydroxyapatite

Steven Verberckmoes, Geert J. Behets, Line Oste et al. · Calcified Tissue International · 2004 · 106 citations

Hydroxyapatite, Physicochemical Characteristics, Bioceramic +2

Localization of lanthanum in bone of chronic renal failure rats after oral dosing with lanthanum carbonate

Geert J. Behets, Steven Verberckmoes, Line Oste et al. · Kidney International · 2005 · 88 citations

Urology, Renal Function, Medicine +6

A multiparameter approach to monitor disease activity in collagen-induced arthritis

Sylvie Seeuws, Peggy Jacques, Jens Van Praet et al. · Arthritis Research & Therapy · 2010 · 81 citations · Full text