Nicolas Desroy

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- <i>a</i> ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis

Nicolas Desroy, Christopher Housseman, Xavier Bock et al. · Journal of Medicinal Chemistry · 2017 · 139 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

F. Moreau, Nicolas Desroy, Jean-Marie Genevard et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 90 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase

Nicolas Desroy, F. Moreau, Sophia Briet et al. · Bioorganic & Medicinal Chemistry · 2008 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-<i>a</i>]pyridine Series of Autotaxin Inhibitors

Agnès Joncour, Nicolas Desroy, Christopher Housseman et al. · Journal of Medicinal Chemistry · 2017 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

From Triclosan toward the Clinic: Discovery of Nonbiocidal, Potent FabI Inhibitors for the Treatment of Resistant Bacteria

Vincent Gerusz, Alexis Denis, Fabien Faivre et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17