Nicolas Desroy

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- <i>a</i> ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis

Nicolas Desroy, Christopher Housseman, Xavier Bock et al. · Journal of Medicinal Chemistry · 2017 · 135 citations · Full text

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

F. Moreau, Nicolas Desroy, Jean-Marie Genevard et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 90 citations

Medicine, Antibacterial Agent, Antimicrobial Chemotherapy +7

Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase

Nicolas Desroy, F. Moreau, Sophia Briet et al. · Bioorganic & Medicinal Chemistry · 2008 · 72 citations · Full text

Hlde Kinase, Medicine, Antiviral Drug Development +4

Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-<i>a</i>]pyridine Series of Autotaxin Inhibitors

Agnès Joncour, Nicolas Desroy, Christopher Housseman et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

From Triclosan toward the Clinic: Discovery of Nonbiocidal, Potent FabI Inhibitors for the Treatment of Resistant Bacteria

Vincent Gerusz, Alexis Denis, Fabien Faivre et al. · Journal of Medicinal Chemistry · 2012 · 54 citations · Full text

Bioorganic Chemistry, Antibiotic Adjuvant, Pharmacotherapy +20