Brooke M. Swalm

The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers

Meagan B. Ryan, Bradley Quade, Natasha Schenk et al. · Cancer Discovery · 2024 · 43 citations · Full text

Medicine, Oncology, Pharmacology +14

Reaction Coupling between Wild-Type and Disease-Associated Mutant EZH2

Brooke M. Swalm, Sarah K. Knutson, Natalie M. Warholic et al. · ACS Chemical Biology · 2014 · 35 citations

Life Sciences, Molecular Biology, Oncology +15

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer

Ryan V. Quiroz, Michael H. Reutershan, Sebastian E. Schneider et al. · Journal of Medicinal Chemistry · 2021 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass Spectrometry

Deborah A. Flusberg, Noreen F. Rizvi, Victoria Kutilek et al. · SLAS DISCOVERY · 2018 · 28 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Development of an automated mid-scale parallel protein purification system for antibody purification and affinity chromatography

Chi Zhang, Alexander Long, Brooke M. Swalm et al. · Protein Expression and Purification · 2016 · 10 citations

Pharmacy, Biochemistry, Biotechnology +14