Bradley Quade

A Plug Release Mechanism for Membrane Permeation by MLKL

Lijing Su, Bradley Quade, Huayi Wang et al. · Structure · 2014 · 220 citations · Full text

Functional synergy between the Munc13 C-terminal C1 and C2 domains

Xiaoxia Liu, Alpay B. Seven, Marcial Camacho et al. · eLife · 2016 · 123 citations · Full text

Membrane bridging by Munc13-1 is crucial for neurotransmitter release

Bradley Quade, Marcial Camacho, Xiaowei Zhao et al. · eLife · 2019 · 117 citations · Full text

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion

E Sitarska, Junjie Xu, Seungmee Park et al. · eLife · 2017 · 97 citations · Full text

The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers

Meagan B. Ryan, Bradley Quade, Natasha Schenk et al. · Cancer Discovery · 2024 · 33 citations · Full text

Ras-mapk Signaling Cascade, Ras–mapk Pathway, Glioma +19