Alpay B. Seven

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Kuglae Kim, Tao Che, Ouliana Panova et al. · Cell · 2020 · 473 citations · Full text

Functional Selectivity, Medicine, Neurotransmitter +3

Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release

Cong Ma, Lijing Su, Alpay B. Seven et al. · Science · 2012 · 426 citations

Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity

Anat Levit, Danielle N. Confair, Kuglae Kim et al. · Nature · 2022 · 240 citations · Full text

Molecular Docking, Bespoke Library Docking, Medicinal Chemistry +9

Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution

Kyle D. Brewer, Taulant Bacaj, Andrea Cavalli et al. · Nature Structural & Molecular Biology · 2015 · 154 citations · Full text

Biophysical Modeling, Molecular Biology, Membrane Biology +4

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD

Can Cao, Ximena Barros-Álvarez, Shicheng Zhang et al. · Neuron · 2022 · 146 citations · Full text

Psychoactive Drug, Psychiatry, Behavioral Neuroscience +14