Halogen-atom and group transfer reactivity enabled by hydrogen tunneling

Timothée Constantin, Bartosz Górski, Michael J. Tilby, +7

Science

EngineeringSynthetic PhotochemistryComputational ChemistryChemistryPhotoredox Process +14

A novel series of positive modulators of the AMPA receptor: Discovery and structure based hit-to-lead studies

Craig Jamieson, Stephanie Basten, Robert A. Campbell, +13

Bioorganic & Medicinal Chemistry Letters

Signal TransductionMolecular PhysiologyBiochemistryNovel SeriesMedicine +11

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF

Timothy M. Chapman, Kevin J. Gillen, Claire Wallace, +10

Bioorganic & Medicinal Chemistry Letters

Genome InstabilityBiochemistryNatural SciencesMolecular BiologyDna Replication +3

Structure based evolution of a novel series of positive modulators of the AMPA receptor

Craig Jamieson, John Maclean, Christopher I. Brown, +12

Bioorganic & Medicinal Chemistry Letters

Signal TransductionMolecular PhysiologyBiochemistryNovel SeriesMedicine +9

A novel series of positive modulators of the AMPA receptor: Structure-based lead optimization

Craig Jamieson, Robert A. Campbell, Iain Cumming, +13

Bioorganic & Medicinal Chemistry Letters

Signal TransductionBiochemistryFunctional SelectivityMedicineStructure-based Lead Optimization +9

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1–XPF

Timothy M. Chapman, Claire Wallace, Kevin J. Gillen, +8

Bioorganic & Medicinal Chemistry Letters

Genome InstabilityBiochemistryNatural SciencesMolecular BiologyAnti-cancer Agent +3

1,3,4(2<i>H</i>)‐isoquinolinetrione herbicides: Novel redox mediators of photosystem I

Glynn Mitchell, Eric D. Clarke, Stuart M. Ridley, +4

Pesticide Science

Redox‐active CompoundsOrganic ChemistryChemistryRedox BiologyOxidative Stress +14

Developing an Antibody–Drug Conjugate Approach to Selective Inhibition of an Extracellular Protein

Elizabeth A. Love, Afrah Sattikar, Hannah Cook, +5

ChemBioChem

ImmunologyNonselective Mmp InhibitorExtracellular ProteinImmunotherapySynthetic Immunology +16

1,3,4(2H)-Isoquinolinetriones: evaluation of amino-substituted derivatives as redox mediator herbicides

Glynn Mitchell, Eric D. Clarke, Stuart M. Ridley, +6

Pest Management Science

Bioorganic ChemistryRedox Mediator HerbicidesOrganic ChemistryChemical DerivativeRedox Biology +14