John Maclean - Concepedia

Author

John Maclean

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID

Also Known As

J. Maclean, J.K.F. Maclean, John K F Maclean, John K. F. Maclean, John K.F. Maclean, John MacLean, John Maclean

Publications

968

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)NHS Lanarkshire Merck (United Kingdom)University of Glasgow International Union of Pure and Applied Chemistry

About

John Maclean is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	15	376
2	Biochemistry	12	13	364
3	Natural Sciences	6	6	142
4	Health Sciences	1	1	24
5	Social Sciences	1	1	28

John Maclean

Publications

908

Citations

H-Index

Page 1

	Year	Citations
Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma Alexander Stoeck, Serguei Lejnine, Andrew Truong, Cancer Discovery	2014	152
Structures of Shikimate Dehydrogenase AroE and Its Paralog YdiB Gurvan Michel, A.W. Roszak, Véronique Sauvé, Journal of Biological Chemistry	2003	115
Biochemical and X‐ray crystallographic studies on shikimate kinase: The important structural role of the P‐loop lysine Tino Krell, John Maclean, Deborah J. Boam, Protein Science	2001	75
The Structure of Chorismate Synthase Reveals a Novel Flavin Binding Site Fundamental to a Unique Chemical Reaction John Maclean, Sohail T. Ali Structure BiosynthesisBiochemistryNatural SciencesChorismate SynthaseEnzyme Catalysis	2003	49
Inhibitors of phosphopantetheine adenylyltransferase Lihua Zhao, Nigel M. Allanson, Samantha P. Thomson, European Journal of Medicinal Chemistry Phosphopantetheine AdenylyltransferaseCellular EnzymologyAldo-keto ReductaseBiochemistryProtein Phosphorylation	2003	46
Positive Allosteric Modulators of the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Simon J. A. Grove, Craig Jamieson, John Maclean, Journal of Medicinal Chemistry	2010	39
Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy Jonathan E. Harms, Morris Benveniste, John Maclean, Neuropharmacology BiochemistryFunctional SelectivityMedicineG Protein-coupled ReceptorRational Drug Design	2012	37
A novel series of positive modulators of the AMPA receptor: Discovery and structure based hit-to-lead studies Craig Jamieson, Stephanie Basten, Robert A. Campbell, Bioorganic & Medicinal Chemistry Letters Signal TransductionMolecular PhysiologyBiochemistryNovel SeriesMedicine	2010	36
Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications Jongwon Lim, Michael D. Altman, James Α. Baker, Bioorganic & Medicinal Chemistry Letters InflammationMedicinal ChemistryDrug TargetKinase 4Anti-inflammatory	2015	32
Discovery of 1-(1<i>H</i>-Pyrazolo[4,3-<i>c</i>]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers Jongwon Lim, Elizabeth H. Kelley, Joey L. Methot, Journal of Medicinal Chemistry Tumor BiologyMedicinal ChemistryUrologyMedicineReceptor Tyrosine Kinase	2016	31

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