Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation

Jean-François Trempe, Véronique Sauvé, Karl Grenier, +10

Science

A Ubl/ubiquitin switch in the activation of Parkin

Véronique Sauvé, Asparouh Lilov, Marjan Seirafi, +7

The EMBO Journal

Mechanism of parkin activation by phosphorylation

Véronique Sauvé, George Sung, Naoto Soya, +6

Nature Structural & Molecular Biology

Signal TransductionSignaling PathwayBiochemistryAutophagyParkin Activation +6

Polo Kinase Regulates Mitotic Chromosome Condensation by Hyperactivation of Condensin DNA Supercoiling Activity

Julie St‐Pierre, Mélanie Douziech, Franck Bazile, +5

Molecular Cell

ChromatinTranscriptional RegulationGenome InstabilityCell DivisionMedicine +7

Structures of Shikimate Dehydrogenase AroE and Its Paralog YdiB

Gurvan Michel, A.W. Roszak, Véronique Sauvé, +5

Journal of Biological Chemistry

The Structure of the RlmB 23S rRNA Methyltransferase Reveals a New Methyltransferase Fold with a Unique Knot

Gurvan Michel, Véronique Sauvé, Robert Larocque, +3

Structure

Rlmb 23SBiochemistryBiomolecular Structure PredictionNatural SciencesUnique Knot +10

The SoxYZ Complex Carries Sulfur Cycle Intermediates on a Peptide Swinging Arm

Véronique Sauvé, Stefano Bruno, Ben C. Berks, +1

Journal of Biological Chemistry

Protein ChemistryBiosynthesisEngineeringBacterial SoxBiochemistry +13

Crystal Structure of Escherichia coli Glucose-1-Phosphate Thymidylyltransferase (RffH) Complexed with dTTP and Mg2+

J. Sivaraman, Véronique Sauvé, Allan Matte, +1

Journal of Biological Chemistry

Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP

J. Sivaraman, Véronique Sauvé, Robert Larocque, +4

Nature Structural Biology

BiosynthesisBiochemistryNatural SciencesProtein X-ray CrystallographyMolecular Biology +3

Parkinson’s disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons

Pingping Song, Wesley Peng, Véronique Sauvé, +10

Neuron

Human Dopaminergic NeuronsNeurodegenerative DiseasesSynaptic PlasticityMolecular NeuroscienceSynaptic Signaling +12