Claire Wallace

Glutamine and macrophage function

Claire Wallace, David Keast · Metabolism · 1992 · 166 citations

Inflammation, Macrophage Biology, Macrophage Function +7

Inhibition of the ERCC1–XPF structure-specific endonuclease to overcome cancer chemoresistance

Ewan M. McNeil, Katy R. Astell, Ann-Marie Ritchie et al. · DNA repair · 2015 · 74 citations · Full text

Medicine, Molecular Biology, Cancer Cell Biology +6

Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development

Judith L. Green, Robert W. Moon, David Whalley et al. · Antimicrobial Agents and Chemotherapy · 2015 · 57 citations · Full text

Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)

Timothy M. Chapman, Simon A. Osborne, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Vitro Adme, Antiparasitic Agent, Malaria +16

Optimization of an Imidazopyridazine Series of Inhibitors of <i>Plasmodium falciparum</i> Calcium-Dependent Protein Kinase 1 (<i>Pf</i>CDPK1)

Timothy M. Chapman, Simon A. Osborne, Claire Wallace et al. · Journal of Medicinal Chemistry · 2014 · 50 citations · Full text

Drug Target, Antiparasitic Agent, Malaria +17