Mark Niosi

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 423 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15

Plasma Protein Binding of Challenging Compounds

Keith Riccardi, Shannon Cawley, Phillip D. Yates et al. · Journal of Pharmaceutical Sciences · 2015 · 117 citations

Pharmacy, Biochemistry, Pharmacology +12

A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats

Gang Wu, Garth T. Whiteside, Gary Lee et al. · European Journal of Pharmacology · 2004 · 86 citations

Medicine, Pharmacology, Pharmacotherapy +16

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Kentaro Futatsugi, Daniel W. Kung, Suvi T. M. Orr et al. · Journal of Medicinal Chemistry · 2015 · 83 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

Kim Huard, Janice A. Brown, Jessica Jones et al. · Scientific Reports · 2015 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11