Ryan Lilien

Probabilistic Disease Classification of Expression-Dependent Proteomic Data from Mass Spectrometry of Human Serum

Ryan Lilien, Hany Farid, Bruce R. Donald · Journal of Computational Biology · 2003 · 172 citations

Engineering, Pathology, Pattern Recognition +19

Network-analysis-guided synthesis of weisaconitine D and liljestrandinine

Christopher J. Marth, Gary M. Gallego, J. C. Lee et al. · Nature · 2015 · 141 citations

Combinatorial Chemistry, Network-analysis-guided Synthesis, Pharmacology +2

The minimized dead‐end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles

Ivelin S. Georgiev, Ryan Lilien, Bruce R. Donald · Journal of Computational Chemistry · 2008 · 139 citations

Protein Assembly, Hybrid Scoring, Biomolecular Structure Prediction +19

A Novel Ensemble-Based Scoring and Search Algorithm for Protein Redesign and Its Application to Modify the Substrate Specificity of the Gramicidin Synthetase A Phenylalanine Adenylation Enzyme

Ryan Lilien, Brian W. Stevens, Amy C. Anderson et al. · Journal of Computational Biology · 2005 · 120 citations

Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

Michael J. Gorczynski, Jolanta Grembecka, Yunpeng Zhou et al. · Chemistry & Biology · 2007 · 117 citations · Full text

Allosteric Inhibition, Protein-protein Interaction, Protein Function +8