P. Brear - Concepedia

Author

P. Brear

University of Cambridge ORCID

Also Known As

Brear, Paul, C. De Fusco, P. Brear, Paul Brear, Paul D. Brear, Paul M. Brear

125

Publications

983

Citations

H-Index

Concepts

All Affiliations

University of Cambridge AstraZeneca (United Kingdom)University of St Andrews Saarland University German Center for Infection Research

About

P. Brear is an author at University of Cambridge specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	113
2	Natural Sciences	3	3	71
3	Biochemistry	3	3	88
4	Engineering	1	1	42
5	Biomedical Engineering	1	1	42

P. Brear

Publications

831

Citations

H-Index

Page 1

	Year	Citations
Specific inhibition of CK2α from an anchor outside the active site P. Brear, Claudia De Fusco, Kathy Hadje Georgiou, Chemical Science	2016	71
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors Maria Reinecke, P. Brear, Larsen Vornholz, Nature Chemical Biology	2023	69
Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in Pseudomonas aeruginosa Audrey Crousilles, Stephen K. Dolan, P. Brear, Journal of Biological Chemistry	2018	67
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066 Claudia De Fusco, P. Brear, Jessica Iegre, Bioorganic & Medicinal Chemistry	2017	63
ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species Linna Zhou, Hironori Ishizaki, Michaela Spitzer, Chemistry & Biology	2012	53
Chain alignment of collagen I deciphered using computationally designed heterotrimers Abhishek A. Jalan, Douglas Sammon, Jeffrey D. Hartgerink, Nature Chemical Biology Tissue EngineeringChain AlignmentEngineeringBiomaterials DesignMolecular Biology	2020	42
Second-generation CK2α inhibitors targeting the αD pocket Jessica Iegre, P. Brear, Claudia De Fusco, Chemical Science	2018	41
Novel non-ATP competitive small molecules targeting the CK2 α/β interface P. Brear, Andrew J. P. North, Jessica Iegre, Bioorganic & Medicinal Chemistry	2018	40
Functional metagenomic screening identifies an unexpected β-glucuronidase Stefanie Neun, P. Brear, E.C. Campbell, Nature Chemical Biology Functional GenomicsUnexpected β-GlucuronidaseBiochemistryGlycosylation	2022	40
A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins Ava S.‐Y. Chen, Nicholas J. Westwood, P. Brear, Molecular Informatics	2016	37

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