Open Targets Platform: new developments and updates two years on

Denise Carvalho‐Silva, Andrea Pierleoni, Miguel Pignatelli, +15

Nucleic Acids Research

EngineeringGenetic EpidemiologySoftware EngineeringBioinformatics DatabaseOpen Platform +23

Open Targets Platform: supporting systematic drug–target identification and prioritisation

David Ochoa, Andrew Hercules, Miguel Carmona, +28

Nucleic Acids Research

Drug TargetTranslational BioinformaticsData ScienceBioinformatics DatabaseMedicine +12

Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

Lauri Peil, Agata L. Starosta, Jürgen Lassak, +7

Proceedings of the National Academy of Sciences

Protein AssemblyMolecular BiologyMolecular GeneticsProtein SynthesisStalled Ribosomes +14

Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

Michaela Spitzer, Emma Griffiths, Kim M. Blakely, +8

Molecular Systems Biology

Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning

Jan Wildenhain, Michaela Spitzer, Sonam Dolma, +7

Cell Systems

EngineeringMachine LearningComputational NeuroscienceMolecular PropertyComputational Biology +4

An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens

Nicole Robbins, Michaela Spitzer, Tennison Yu, +7

Cell Reports

Immune disease variants modulate gene expression in regulatory CD4+ T cells

Lara Bossini‐Castillo, Dafni A. Glinos, Natalia Kunowska, +15

Cell Genomics

Zebrafish MITF-Low Melanoma Subtype Models Reveal Transcriptional Subclusters and MITF-Independent Residual Disease

Jana Trávníčková, Sonia Wojciechowska, Ava Khamseh, +15

Cancer Research

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

Linna Zhou, Hironori Ishizaki, Michaela Spitzer, +14

Chemistry & Biology

Combined zebrafish-yeast chemical-genetic screens reveal gene–copper-nutrition interactions that modulate melanocyte pigmentation

Hironori Ishizaki, Michaela Spitzer, Jan Wildenhain, +9

Disease Models & Mechanisms