Jessica Iegre

A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066

Claudia De Fusco, P. Brear, Jessica Iegre et al. · Bioorganic & Medicinal Chemistry · 2017 · 63 citations · Full text

Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells

Tiziano Tuccinardi, Carlotta Granchi, Jessica Iegre et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 48 citations · Full text

Oncology, Biochemistry, Medicine +8

Two‐Component Stapling of Biologically Active and Conformationally Constrained Peptides: Past, Present, and Future

Jessica Iegre, Josephine Gaynord, Naomi Robertson et al. · Advanced Therapeutics · 2018 · 47 citations

Stapling Technique, Protein Assembly, Biologically Active +24

Second-generation CK2α inhibitors targeting the αD pocket

Jessica Iegre, P. Brear, Claudia De Fusco et al. · Chemical Science · 2018 · 41 citations · Full text

Novel non-ATP competitive small molecules targeting the CK2 α/β interface

P. Brear, Andrew J. P. North, Jessica Iegre et al. · Bioorganic & Medicinal Chemistry · 2018 · 40 citations · Full text