Paul W.G. Wijnhoven

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

Carmen Adriaens, Laura Standaert, Jasmine Barra et al. · Nature Medicine · 2016 · 475 citations

Life Sciences, Genetics, Molecular Biology +16

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity

Jacqueline H. L. Fok, Antonio Ramos‐Montoya, Mercedes Vázquez–Chantada et al. · Nature Communications · 2019 · 334 citations · Full text

Medicine, Oncology, Radiation Oncology +17

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

Mohammad Asim, Firas Tarish, Heather Zecchini et al. · Nature Communications · 2017 · 278 citations · Full text

Medicine, Molecular Biology, Oncology +17

Combined PARP and ATR inhibition potentiates genome instability and cell death in ATM-deficient cancer cells

Rebecca L. Lloyd, Paul W.G. Wijnhoven, Antonio Ramos‐Montoya et al. · Oncogene · 2020 · 186 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

Ryotaro Nishi, Paul W.G. Wijnhoven, Carlos le Sage et al. · Nature Cell Biology · 2014 · 151 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +4