Maria Cecilia Palumbi

Discovery of 2-{4-[(3<i>S</i>)-Piperidin-3-yl]phenyl}-2<i>H</i>-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors

Philip Jones, Sergio Altamura, Julia K. Boueres et al. · Journal of Medicinal Chemistry · 2009 · 315 citations · Full text

Medicine, Oncology, Pharmacology +16

Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

Ester Muraglia, Olaf Kinzel, Ralph Laufer et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 90 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Identification of Novel, Selective, and Stable Inhibitors of Class II Histone Deacetylases. Validation Studies of the Inhibition of the Enzymatic Activity of HDAC4 by Small Molecules as a Novel Approach for Cancer Therapy

Jesus M. Ontoria, Sergio Altamura, Annalise Di Marco et al. · Journal of Medicinal Chemistry · 2009 · 61 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors

Federica Orvieto, Danila Branca, Claudia Giomini et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 55 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +11

2-Trifluoroacetylthiophene oxadiazoles as potent and selective class II human histone deacetylase inhibitors

Ester Muraglia, Sergio Altamura, Danila Branca et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 53 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9