Christopher D. Scharer

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

Scott A. Jenks, Kevin S. Cashman, Esther Zumaquero et al. · Immunity · 2018 · 1K citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +10

Sex-Determining Region Y Box 4 Is a Transforming Oncogene in Human Prostate Cancer Cells

Pengbo Liu, Sumathi Ramachandran, Mohamed Ali‐Seyed et al. · Cancer Research · 2006 · 298 citations

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

Masao Hashimoto, Koichi Araki, Maria A. Cardenas et al. · Nature · 2022 · 293 citations · Full text

Autoimmune Disease, T-regulatory Cell, Immunology +8

Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway

Rheinallt M. Jones, Chirayu Desai, Trevor Darby et al. · Cell Reports · 2015 · 220 citations · Full text

Hormetic Adaptation, Dysbiosis, Host-microbe Interactions +23

Epigenetic programming underpins B cell dysfunction in human SLE

Christopher D. Scharer, Emily L. Blalock, Mi Tian et al. · Nature Immunology · 2019 · 203 citations · Full text

Chromatin, Epigenetic Change, Genetics +5