Sami Haddad

A PBPK Modeling-Based Approach to Account for Interactions in the Health Risk Assessment of Chemical Mixtures

Sami Haddad · Toxicological Sciences · 2001 · 125 citations

Exposure Assessment, Mixture Exposures, Physiologically-based Pharmacokinetic Modeling +25

Relative lipid content as the sole mechanistic determinant of the adipose tissue:blood partition coefficients of highly lipophilic organic chemicals

Sami Haddad, Patrick Poulin, Kannan Krishnan · Chemosphere · 2000 · 123 citations

Obesity, Metabolic Syndrome, Lipid Analysis +13

Physiological Modeling of Age-Specific Changes in the Pharmacokinetics of Organic Chemicals in Children

Karine Price, Sami Haddad, Kannan Krishnan · Journal of Toxicology and Environmental Health · 2003 · 117 citations

CHARACTERIZATION OF AGE-RELATED CHANGES IN BODY WEIGHT AND ORGAN WEIGHTS FROM BIRTH TO ADOLESCENCE IN HUMANS

Sami Haddad, C Restieri, Kannan Krishnan · Journal of Toxicology and Environmental Health · 2001 · 107 citations

Nutrition, Young Adult Development, Aging +17

In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods

Patrick Poulin, Jane R. Kenny, Cornelis E. C. A. Hop et al. · Journal of Pharmaceutical Sciences · 2011 · 105 citations

Physiologically-based Pharmacokinetic Modeling, Pharmacodynamic Modeling, Vitro–in Vivo Extrapolation +16