Masako Wakitani

Establishment of <i>FUT8</i> knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity

Naoko Yamane‐Ohnuki, Satoko Kinoshita, Miho Inoue‐Urakubo et al. · Biotechnology and Bioengineering · 2004 · 566 citations

Allergy, Autoimmune Disease, Medicine +15

Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

Akira Okazaki, Emi Shoji-Hosaka, Kazuyasu Nakamura et al. · Journal of Molecular Biology · 2004 · 334 citations

Biochemistry, Immune Regulation, Immunology +6

IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides

Rinpei Niwa, Akito Natsume, Aya Uehara et al. · Journal of Immunological Methods · 2005 · 235 citations · Full text

Nonfucosylated Therapeutic IgG1 Antibody Can Evade the Inhibitory Effect of Serum Immunoglobulin G on Antibody-Dependent Cellular Cytotoxicity through its High Binding to FcγRIIIa

Shigeru Iida, Hirofumi Misaka, Miho Inoue et al. · Clinical Cancer Research · 2006 · 206 citations · Full text

Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities

Akito Natsume, Mika In, Hiroyuki Takamura et al. · Cancer Research · 2008 · 186 citations · Full text

Immunocytochemical Technique, Engineering, Immunology +20