K. Kosovrasti

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Publications

Citations

248

H-Index

Active since

2018

Affiliations

University of Massachusetts Chan Medical School(Current)

University of North Carolina at Chapel Hill

K. Kosovrasti is an author at University of Massachusetts Chan Medical School specializing in molecular virology, virology, and antiviral drug resistance.

ORCID

Publications per year

2018–2023

Publications

Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance

M. Henes, G.J. Lockbaum, K. Kosovrasti et al. · ACS Chemical Biology · 2019 · 44 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease

G.J. Lockbaum, Florian Leidner, L.N. Rusere et al. · ACS Infectious Diseases · 2018 · 34 citations

Life Sciences, Biochemistry, Molecular Biology +17

HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2′ Ligands To Optimize Hydrogen Bonding in the Substrate Envelope

L.N. Rusere, G.J. Lockbaum, Sook-Kyung Lee et al. · Journal of Medicinal Chemistry · 2019 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

Ashley N. Matthew, Jacqueto Zephyr, Desaboini Nageswara Rao et al. · mBio · 2020 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Inhibiting HTLV-1 Protease: A Viable Antiviral Target

G.J. Lockbaum, M. Henes, Nathaniel Talledge et al. · ACS Chemical Biology · 2021 · 23 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +17

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