Ashley N. Matthew

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Publications

Citations

164

H-Index

Active since

2017

Affiliations

University of Massachusetts Chan Medical School(Current)

Ashley N. Matthew is an author at University of Massachusetts Chan Medical School specializing in medicinal chemistry, pharmacology, and antiviral drug resistance.

ORCID

Publications per year

2017–2022

Publications

Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants

Ashley N. Matthew, Jacqueto Zephyr, Caitlin. J. Hill et al. · Journal of Medicinal Chemistry · 2017 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Quinoxaline-Based P1–P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants

Desaboini Nageswara Rao, Jacqueto Zephyr, M. Henes et al. · Journal of Medicinal Chemistry · 2021 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

Ashley N. Matthew, Jacqueto Zephyr, Desaboini Nageswara Rao et al. · mBio · 2020 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease

Ashley N. Matthew, Florian Leidner, Alicia Newton et al. · Structure · 2018 · 23 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +15

Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants

L.N. Rusere, Ashley N. Matthew, G.J. Lockbaum et al. · ACS Medicinal Chemistry Letters · 2018 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

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