Concepedia

M. Henes

MH

12

Publications

295

Citations

11

H-Index

2018

Active since

Affiliations

University of Massachusetts Chan Medical School(Current)

University of North Carolina at Chapel Hill

M. Henes is an author at University of Massachusetts Chan Medical School specializing in medicine, drug discovery, and molecular biology.

ORCID

Top concepts

Publications per year

2018–2023

12

Publications

12

Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance

M. Henes, G.J. Lockbaum, K. Kosovrasti et al. · ACS Chemical Biology · 2019 · 44 citations · Full text

, , +17

Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode

G.J. Lockbaum, M. Henes, Jeong Min Lee et al. · Biochemistry · 2021 · 35 citations · Full text

Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease

G.J. Lockbaum, Florian Leidner, L.N. Rusere et al. · ACS Infectious Diseases · 2018 · 34 citations

, , +19

HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2′ Ligands To Optimize Hydrogen Bonding in the Substrate Envelope

L.N. Rusere, G.J. Lockbaum, Sook-Kyung Lee et al. · Journal of Medicinal Chemistry · 2019 · 29 citations · Full text

Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors

Ashley N. Matthew, Jacqueto Zephyr, Desaboini Nageswara Rao et al. · mBio · 2020 · 25 citations · Full text

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