Concepedia

Florian Leidner

FL

11

Publications

287

Citations

11

H-Index

2017

Active since

Affiliations

University of Massachusetts Chan Medical School(Current)

Florian Leidner is an author at University of Massachusetts Chan Medical School specializing in molecular biology, medicine, and drug discovery.

Top concepts

MedicineMolecular BiologyDrug DiscoveryNatural SciencesSystems BiologyHivImmunologyMolecular ModelingVirologyBiochemistry

Publications per year

2017–2021

11

Publications

11

Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance

M. Henes, G.J. Lockbaum, K. Kosovrasti et al. · ACS Chemical Biology · 2019 · 44 citations · Full text

Molecular Biology, Distal Mutations, Antiviral Drug +17

Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 Protease

Florian Leidner, Neşe Kurt Yılmaz, Janet L. Paulsen et al. · Journal of Chemical Theory and Computation · 2018 · 35 citations · Full text

Engineering, Protein Assembly, Hydration Structure +19

Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease

G.J. Lockbaum, Florian Leidner, L.N. Rusere et al. · ACS Infectious Diseases · 2018 · 34 citations

Immunology, Molecular Biology, Analytical Ultracentrifugation +19

Interdependence of Inhibitor Recognition in HIV-1 Protease

Janet L. Paulsen, Florian Leidner, Debra A. Ragland et al. · Journal of Chemical Theory and Computation · 2017 · 29 citations

Molecular Docking, Protein Chemistry, Hiv-1 Protease +15

Target-Specific Prediction of Ligand Affinity with Structure-Based Interaction Fingerprints

Florian Leidner, Neşe Kurt Yılmaz, Celia A. Schiffer · Journal of Chemical Information and Modeling · 2019 · 27 citations · Full text

Drug Target, Machine Learning Methodology, Molecular Biology +17

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