Scott D. Cowen

Structural Basis of Substrate Methylation and Inhibition of SMYD2

Andrew D. Ferguson, Nicholas Larsen, Tina Howard et al. · Structure · 2011 · 193 citations · Full text

Biochemistry, Natural Sciences, Epigenetic Change +7

Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B through Structure-Based Drug Design

Paul D. Greenspan, Kirk Clark, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 2001 · 136 citations · Full text

Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases

Tao Wang, Michael A. Block, Scott D. Cowen et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 45 citations · Full text

Tbk1/ikkε Kinases, Medicinal Chemistry, Drug Target +13

Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors

Scott D. Cowen, Daniel Russell, Leslie Dakin et al. · Journal of Medicinal Chemistry · 2016 · 36 citations · Full text

Histone Modifications, Epigenetic Change, Molecular Biology +24

Syntheses of 5a‘-<i>h</i><i>omo</i>-Vinblastine and Congeners Designed to Establish Structural Determinants for Isolation of Atropisomers

Martin E. Kuehne, Scott D. Cowen, Feng Xu et al. · The Journal of Organic Chemistry · 2001 · 33 citations

Molecular Biology, Organic Chemistry, Chemistry +17