Richard Melton

Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

Lauren G. Monovich, Rubén Tommasi, Roger A. Fujimoto et al. · Journal of Medicinal Chemistry · 2009 · 56 citations · Full text

Active Carboxylic Acid, Type Ii Collagen, Chemical Biology +19

Inhibition of interleukin-1?-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors: Potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid

Vishwas Ganu, Ronald Goldberg, Jane Peppard et al. · Arthritis & Rheumatism · 1998 · 54 citations

Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1 1 1Edited by P. E. Wright

Xiaolu Zhang, Nina C. Gonnella, James A. Koehn et al. · Journal of Molecular Biology · 2000 · 39 citations

Human Collagenase-3, Catalytic Domain, Biochemistry +11

Solution Structure of the Catalytic Domain of Human Stromelysin-1 Complexed to a Potent, Nonpeptidic Inhibitor

Yu-Chin Li, Xiaolu Zhang, Richard Melton et al. · Biochemistry · 1998 · 35 citations