Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

Hamid Nikbakht, Eshini Panditharatna, Leonie G. Mikael, +21

Nature Communications

Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy

Eshini Panditharatna, Lindsay Kilburn, Mariam Aboian, +17

Clinical Cancer Research

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

Surya Nagaraja, Michael A. Quezada, Shawn Gillespie, +9

Molecular Cell

Histone ModificationsChromatinChromatin RemodelingOncogenic StateGenetics +9

Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes

Amanda Saratsis, Madhuri Kambhampati, Kendall Snyder, +12

Acta Neuropathologica

Neuro-oncologyTumor BiologyPediatric Brain TumorsMolecular SubtypesTumor Heterogeneity +9

Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition

Isabella Taylor, Marianne Hütt-Cabezas, William D. Brandt, +6

Journal of Neuropathology & Experimental Neurology

High-grade GliomasRadiation BiologyCancer BiologyGliomaTumor Biology +23

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

Hiroaki Miyahara, Sridevi Yadavilli, Manabu Natsumeda, +10

Cancer Letters

GliomaRadiation TherapyMedicineEnhances RadiosensitizationAnti-cancer Agent +7

Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003

Cassie Kline, Payal Jain, Lindsay Kilburn, +25

Clinical Cancer Research

A standardized autopsy procurement allows for the comprehensive study of DIPG biology

Madhuri Kambhampati, Jennifer Pérez, Sridevi Yadavilli, +7

Oncotarget

Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma

Shejuan An, Jeannie M. Camarillo, Tina Yi-Ting Huang, +10

Journal of Experimental & Clinical Cancer Research

The emerging role of NG2 in pediatric diffuse intrinsic pontine glioma

Sridevi Yadavilli, Joseph Scafidi, Oren J. Becher, +10

Oncotarget