Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

Humsa S. Venkatesh, Tessa Johung, Viola Caretti, +13

Cell

Neuro-oncologyNeuroregenerationGliomaBrain Tumor BiologyNeural Stem Cell +7

c-Jun overexpression in CAR T cells induces exhaustion resistance

Rachel C. Lynn, Evan W. Weber, Elena Sotillo, +16

Nature

PhysiologyAutoimmunityTolerance InductionImmunotherapyMedicine +4

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

Humsa S. Venkatesh, Lydia Tam, Pamelyn J. Woo, +9

Nature

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma

Surya Nagaraja, Nicholas A. Vitanza, Pamelyn J. Woo, +13

Cancer Cell

Neuro-oncologyGliomaTumor HeterogeneityTranscriptional DependenciesMedicine +3

Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment

Erin M. Gibson, Surya Nagaraja, Alfonso Ocampo, +12

Cell

Neuro-oncologyNeuropsychologyAlzheimer's DiseaseDementiaNeuropharmacology +8

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening

Grant L. Lin, Kelli M. Wilson, Michele Ceribelli, +30

Science Translational Medicine

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma

Elizabeth Y. Qin, Dominique D. Cooper, Keene L. Abbott, +7

Cell

Neuro-oncologyMolecular NeuroscienceEpendymaNeuroanatomyBrain Tumor Biology +5

Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex

Ana Uzquiano, Amanda J. Kedaigle, Martina Pigoni, +16

Cell

Proper AcquisitionCell LineageHuman CellDevelopmental BiologyFate Specification Programs +11

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

Surya Nagaraja, Michael A. Quezada, Shawn Gillespie, +9

Molecular Cell

Histone ModificationsChromatinChromatin RemodelingOncogenic StateGenetics +9

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma

Grant L. Lin, Surya Nagaraja, Mariella G. Filbin, +3

Acta Neuropathologica Communications