Laura Breda

Reactivation of Developmentally Silenced Globin Genes by Forced Chromatin Looping

Wulan Deng, Jeremy Rupon, Ivan Krivega et al. · Cell · 2014 · 437 citations · Full text

Chromatin, Developmental Biology, Chromatin Structure +13

Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

Sara Gardenghi, Maria Franca Marongiu, Pedro Luiz Ramos et al. · Blood · 2007 · 313 citations · Full text

In vivo hematopoietic stem cell modification by mRNA delivery

Laura Breda, Tyler E. Papp, Michael Triebwasser et al. · Science · 2023 · 265 citations · Full text

Cell Therapy, Novel Therapy, Hsc Transplantation +15

Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia

Pedro Luiz Ramos, Carla Casu, Sara Gardenghi et al. · Nature Medicine · 2013 · 231 citations · Full text

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

Sara Gardenghi, Pedro Luiz Ramos, Maria Franca Marongiu et al. · Journal of Clinical Investigation · 2010 · 218 citations · Full text

Iron Metabolism, Excessive Iron Absorption, Iron Deficiency +20